Wednesday, 5 December 2018

Did You Know?
The era of genetically modified babies/ humans is here. We may soon have X-Men mutants and Superheroes in future. Who knows? 

CRISPR babies: more details on the experiment that shocked the world


On Monday, the world was stunned by an Associated Press story claiming that the first gene-edited babies had been born in China. On Wednesday, the scientist responsible revealed far more details during a talk at a gene-editing summit in Hong Kong, including that there is another pregnancy.
There hasn’t yet been any independent verification that two gene-edited girls really have been born. But the technical details revealed by He Jiankui today may have been enough to convince many of the scientists in attendance. However, questions still remain over the ethics and safety of the experiment.
The stated aim of the project was to make individuals immune to HIV by disabling the gene for a protein called CCR5, which is exploited by the virus. However, disabling this gene does not provide complete protection against HIV and the broader consequences of knocking out this gene – which is involved in immune function – are unclear.

Inadvertent enhancement

The team began by using the CRISPR gene editing method to disable CCR5 in mice and monkeys, He said, and found no health or behavioural issues. But one of the organisers of the summit, Robin Lovell-Badge of the Francis Crick Institute in London, pointed out that immune genes affect the entire body, and that a different mouse study found that deleting CCR5 improved their cognitive abilities.
“Have you inadvertently caused an enhancement?” Lovell-Badge asked He after the talk. The mouse study needed verification, He replied. “I am against using genome editing for enhancement.”
Read through the article to know the details.

Monday, 12 November 2018

Stephen Hawking Said 'Superhumans'  Will Replace Us. 

Was He Right?
Are we all going to be replaced?
Stephen Hawking apparently thought so. In the grand tradition of famous physicists making claims about subjects beyond their scope of expertise, the great British theorist left behind a collection of essays in which he speculated about and predicted the human future. In one essay, published Oct. 14 in the Sunday Times, Hawking argued that humanity risks being replaced by genetically modified "superhumans."

Well-intentioned research designed to improve human health and human life, he wrote, will eventually be corrupted. People will start to modify humans to live longer, be smarter, or be more aggressive and dangerous. [9 Absolutely Evil Medical Experiments]

Was Hawking right to worry about this sort of dystopia?



"Once such superhumans appear, there are going to be significant political problems with the unimproved humans, who won't be able to compete," Hawking wrote. "Presumably, they will die out, or become unimportant."
Was Hawking right to worry about this sort of dystopia?
The physicist framed the problem in startling terms. But he's not alone in worrying that humanity is wandering into dangerous territory as genetic technologies improve.
Right now, the gene editing available for humans almost exclusively treats severe medical problems. For incurable, deadly diseases, doctors have altered people's genes to prevent those diseases from progressing further. This has sometimes been successful, as Live Science has previously reported. There have also been early experiments in China into germline gene editing — making genetic changes that can be passed down from one generation to the next — in order to prevent parents from passing genetic diseases to their children.
Bioethicists have raised concerns about where all this is headed.
The most immediate concerns, though, aren't about superhumans. The first problem with gene therapy is that it's just not that well understood, according to the National Human Genome Research Institute (NHGRI). Researchers don't yet know all the possible side effects of gene editing, or the risk of those changes being passed from one generation to the next.
Relatedly, according to the NHGRI, "In germline gene transfer, the persons being affected by the procedure — those for whom the procedure is undertaken — do not yet exist. Thus, the potential beneficiaries are not in a position to consent to, or refuse, such a procedure."
However, if gene editing were to become widespread, there's a risk it would be available only to the wealthy, and that efforts to prevent genetic diseases could blur with efforts to create enhanced humans, according to the National Institutes of Health.

The University of Missouri Center for Health Ethics similarly published a document online raising the possibility that efforts to weed out genetic diseases could de facto lead to the eugenic eradication of disabled people from society. And, according to the Center, in a society where human beings are enhanced, previous "models" of human risk become obsolete, echoing Hawking's fear.
But the closer a bioethical argument gets to the world Hawking envisioned, the vaguer the predictions become — because the science is still a long way off from that point. And right now, this sort of conversation often amounts to confusing scaremongering, said Matthew Willmann a biologist and director of the Plant Transformation Facility at Cornell University.
"I was frustrated [to read what Hawking wrote] because, to me, if you want to scare people about a technology that has some amazingly positive benefits for humankind, you'd make predictions like that," he told Live Science. [10 Amazing Things Scientists Just Did with CRISPR]
It's theoretically possible that Hawking's world of superhumans could emerge, Willmann said.
"Could it happen? Yeah. But there's a lot going on to prevent that from happening," he said.
Scientific institutions and governments are developing strict ethical codes and laws that would regulate gene editing, he pointed out. And those laws would be incredibly difficult to circumvent without the world noticing.
In the TV show "Orphan Black," a cabal of scientists decide to edit and enhance a group of cloned babies — and all the scientists need is money and a willingness to do evil things.
But the reality, Willmann pointed out, is that genetics is too complicated and confusing for that to work.
"You can only do editing when you have information about how the genes work," he said.
In his research, he's able to create plants with specific genetic traits only by first creating lots of plants with damaged, deadly, or otherwise screwed-up genes. Over time, he and his colleagues figure out which genes do what and therefore how those genes need to be modified to get the results they want.
But that's only possible, he said, because, "as I often say, plants don't cry."
A similar project in human beings would take far longer, and be — if not unimaginable — difficult to pull off in a modern society.
So, was Hawking right to worry about a new species of superhumans replacing our own? It's hard to definitively say no. But it's probably not going to happen anytime soon, and there are more pressing ethical concerns in genetics to worry about in the meantime, Willmann said.
Originally published on Live Science
https://www.livescience.com/63838-hawking-superhumans-will-replace-us.html?fbclid=IwAR0674dPW4-PEXcMux4ariaz7wS028tUyttWb9JLW9_XIv3i9NEBFAgZq9o 

Monday, 29 October 2018

eBooks and Their Advantages

Simply put, eBooks are books that are available in digital format. The major advantage of eBooks is that they are eco-friendly as they do not require trees to be cut down for produce or manufacture them. Most of PHI Learning titles are now also available in eBook format. These eBooks can be ordered online and delivered electronically to your computer.

•Our eBooks are available as Adobe Digital Edition (not pdf format).
•Can be read in laptop, desktop as well as mobiles.
•Ideal for individual use.
•Option to recover eBook/s lost due to system crash.
•Our eBooks come with perpetual license unless a new edition is released.





To know more about PHI Learning eBooks log on to our website https://www.phindia.com/PHI/AboutEbooks

Friday, 26 October 2018

Astronomers May Have Spotted Another Neutron Star Merger



In 2017, gravitational waves and light were observed coming from the merger of a pair of neutron stars. The discovery proved that gravitational wave sources could also be viewed at visible, X-ray, and even gamma-ray wavelengths, but has remained the only such event observed to date. Now, researchers have identified a “cosmic look-alike” — an event they believe came from the same type of system as the one that produced the gravitational waves.

Seeing Double

Such a discovery would double the number of known events of this type. “It’s a big step to go from one detected object to two,” said Eleonora Troja of NASA’s Goddard Space Flight Center, and lead author of the study published October 16 in Nature Communications, in a press release. The paper focuses on a gamma-ray burst, called GRB 150101B, seen by NASA’s Neil Gehrels Swift Observatory in 2015. Troja’s team followed up using NASA’s Chandra X-ray Observatory, Fermi Gamma-ray Space Telescope, Hubble Space Telescope, and the Discovery Channel Telescope to determine that GRB 150101B appears similar to the 2017 gravitational wave event GW170817, which was produced by a kilonova that occurred when two inspiralling neutron stars collided. Shortly after that event’s gravitational waves reached Earth, astronomers also spotted a gamma-ray burst and light at several wavelengths associated with the merger, proving that neutron star mergers are capable of producing all these signals.
During a neutron star merger, astronomers believe a narrow jet of high-energy particles is created, which is responsible for the short burst of gamma rays spotted from Earth. In the case of both GW170817 and GRB 150101B, that jet was likely viewed off-axis, meaning it was not directly pointed toward our planet, because the bursts were fainter and shorter lived than expected. Both events also generated bright blue light at visible wavelengths (the kilonova) and lasting X-ray emission. The two even came from host galaxies that look similar: old elliptical galaxies with no newly forming stars.
Read more at 

Wednesday, 3 October 2018

“It’s OK not to be OK”

“It’s OK not to be OK”. Abilities have different contours, and have shaped the destiny of mankind beyond imagination. 

Dyslexia is one such ability which deprives a child of a ‘Reading Brain’. Though gifted with an ability to understand complex ideas, the manner in which the dyslexics grasp and comprehend information makes them unique and differential. An educator dealing with such creative individuals has to think out of the box making the learning environment more inclusive and encouraging at all times. Bringing such learners from the margin to the mainstream shall be based on the principle that “Every student can learn , may be just not on the same day or the same way”.

The book- “ Educating Exceptional Children- An Introduction to special Education”, by      Dr. S.K. Mangal, not only provides an insightful and vivid discussion on various aspects of special learners both cognitively impaired and learning impaired but it also presents practical experiences of special educators in the form of case studies.

The book lays emphasis on harnessing the innate potential of each learner by the educator and provides a plethora of ideas and techniques to do wonders with such learners. The book follows the Ethos: “All people see the disabilities, but a special educator unleashes the possibilities.”



Dyslexia Awareness Workshop and 
DALI App Launch
October 5, 2018 
IIC Annexe, Lecutre Hall 2
9.30 - 11.30 AAM
Register Today
Free Registration; Limited Seats



Friday, 14 September 2018


हिंदी दिवस की हार्दिक शुभकामनायें !




हमारी हिन्दी पुस्तकों के बारे में जानकारी और क्रय करने के लिये क्लिक करें https://www.phindia.com/Books/BookInHindi

PHI Learning Ebooks Available 
on Amazon Kindle



Monday, 3 September 2018

ENGINEERING HYDROLOGY
by Manish Kumar Goyal


The book has GATE questions also. 




Purchase this book written by IIT Indore faculty from our website
https://www.phindia.com/Books/BookDetail/OTc4LTgxLTIwMy01MjQzLTg  

Wednesday, 6 June 2018

Celebrating Foundation Day Today

Celebrating 55 Successful Years 
of Publishing

Celebrating 55 Years 
of Helping Teachers to Teach and Students to Learn 
with Eastern Economy Editions

PHI pioneered Eastern Economy Editions for publishing low-cost quality texts at affordable price. On the road to fifty-five successful years of publishing, PHI has published more than 5000 titles in virtually all disciplines. Many of these books are adopted at premier institutions in India and abroad, and have been translated into foreign languages.


To know more about us, log on to www.phindia.com

Thursday, 31 May 2018

New Book Announcement

CORPORATE FINANCIAL REPORTING AND ANALYSIS
by Dr. Asish K. Bhattacharyya

HIGHLIGHTS OF THE BOOK

• Case study-based approach.

• Ind AS revised up to March 31, 2018, including Ind AS15.

• Schedule III of the Companies Act, 2013.

• Use of financial statements of HUL, Infosys and Suzlon for the year 2016–17 throughout the text to explain Schedule III, accounting principles and financial statement analysis.

• Numerous illustrations and self-test questions (with answers) after each concept for students to assess their knowledge and grasping.

• Chapter-end assignments including multiple choice questions, fill in the blanks, analytical questions and problems for practice.

 Corporate Financial Reporting and Accounting

For more details on the book, log on to


Wednesday, 30 May 2018

New Book Announcement
New Fourth Edition Released of Our Book on Business Law

Laws for Business, Fourth Edition
by M. M. Sulphey and Az-Har Basheer

NEW TO THIS EDITION
• Chapter on Value Added Tax has been replaced with a new chapter on The Central Goods and Services Tax Act, 2017 (Chapter 29).
• Includes a new chapter on The Sexual Harassment of Women at Workplace (Prevention, Prohibition and Redressal) Act, 2013.
• Employees' State Insurance Act, 1948 (Chapter 19) and Employees' Provident Funds and Miscellaneous Provisions Act, 1952 (Chapter 20) have been updated.




 Laws for Business



For more information, log on to
https://www.phindia.com/Books/BookDetail/OTc4LTkzLTg3NDcyLTY3LTk

Tuesday, 17 April 2018

Mr. Asoke Ghosh, Chairman and Managing Director 
PHI Learning awarded 
Simon Master Chairman's Award 
given for excellence in global publishing

We take pride in sharing news of another award for our Chairman and Managing Director, Mr. Asoke Ghosh,the Simon Master Chairman's Award which was conferred on him at the London Book Fair on Tuesday, 10th April 2018 for his contribution and impact on global publishing.



With this award he joins the list of the such previous awardees as
  • His Highness Dr. Shaikh Sultan Bin Mohamad Al Qasimi, Supreme Council Member and Ruler of Sharjah, 2017
  • Ernest Hecht, British Publisher, producer and Philanthropist who founded Souvenir Press Ltd., 2016
  • China Publishing Group, 2015

Monday, 9 April 2018

A MOMENT OF PRIDE!

It’s a moment of pride and great honour for PHI Learning that its Chairman and Managing Director, Mr. Asoke K. Ghosh, has been conferred an honorary title of President Emeritus by the Federation of Indian Publishers (FIP). This prestigious title has been awarded to Mr. Ghosh on joint proposal and recommendation of the members of FIP to acknowledge his services and contribution to the Federation and the publishing sector as a whole.
As a key founder member and the Past President of FIP, Mr. Ghosh has fulfilled his responsibilities and duties conscientiously, which has been appreciably recognized by the Federation from time to time. For his selfless contribution towards education and book publishing industry, the Federation conferred on him the Life Time Achievement Award in 2012, besides innumerable prestigious awards and laurels including Most Distinguished Publisher Award and Saraswati Samman.

Mr. Ghosh is the first Asian to become the Vice President of International Publishers Association (IPA). In 1991, IPA bestowed on him Outstanding Leadership Award. He was Instrumental in bringing the 24th IPA Congress to New Delhi in 1992 for the first time, and played a major role in organizing and successfully leading 32nd IPA Congress in February 2018. It was largely due to Mr. Ghosh’s effort that Delhi was declared World Book Capital for the year 2003 by UNESCO, and today Indian publishing has emerged as a significant market among the leading players at the global platform.

Monday, 2 April 2018

Know the Author

Prof. R. Narayanaswamy, Business Today named him among the best business school professors.



PHILearning book written by Prof. Narayanaswamy
FINANCIAL ACCOUNTING: A MANAGERIAL PERSPECTIVE, Sixth Edition

https://www.phindia.com/Books/BookDetail/OTc4LTgxLTIwMy01MzQzLTU 

R. NARAYANASWAMY (PhD, UNSW, Sydney) is Professor of Finance and Control at Indian Institute of Management Bangalore, Visiting Fellow at Manchester Business School and Osaka University. He is a Chartered Accountant, Cost Accountant and Company Secretary and holds the ICAI’s Diploma in Management Accountancy.

He published in national and international journals, including Accounting Horizons, The British Accounting Review, The International Journal of Accounting, Journal of Accounting, Auditing and Finance, The Journal of International Financial Management and Accounting, Research in Accounting Regulation and Accountancy. He contributed a chapter on India in Globalisation of Accounting Standards published by Edward Elgar Publishing, UK., He has served on the board and audit committee of Indian Railway Finance Corporation Limited and Bank of Baroda and on the ICAI’s Accounting Standards Board and the Auditing and Assurance Standards Board. 

http://www.iimb.ac.in/user/84/r-narayanaswamy




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Success as a manager will primarily depend on Soft Skills. What is this talent that means more than experience and technical prowess ...